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Table 2 gives the incidence of treatment-emergent adverse reactions in placebo-controlled trials for approved indications that occurred in 5or more of patients treated with CYMBALTA and with an incidence greater than placebo.
Approximately 17.5227/1294of the patients who received CYMBALTA in 3 to 6 month placebo-controlled trials for FM discontinued treatment due to an adverse reactioncompared with 10.196/955for placeboCommon adverse reactions reported as a reason for discontinuation and considered to be drug-relatedas defined aboveincluded nauseaCYMBALTA 2.0placebo 0.5headacheCYMBALTA 1.2placebo 0.3somnolenceCYMBALTA 1.1placebo 0.0and fatigueCYMBALTA 1.1placebo 0.1
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a medical effect of cymbalta occurs in 3-4 weeks after the beginning of the treatment.
