Bupron sr bupropion hydrochloride when taken in a large dose, are likely to cause seizures.
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No matter what your agebefore you take an antidepressantyouyour parentor your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatmentsYou should also talk about the risks and benefits of not treating your conditionYou should know that having depression or another mental illness greatly increases the risk that you will become suicidalespecially at the beginning of your treatment or any time that your dose is increased or decreasedThis risk is higher if you or anyone in your family has or has ever had bipolar disorder or mania or has thought about or attempted suicideTalk to your doctor about your conditionsymptomsand personal and family medical historyYou and your doctor will decide what type of treatment is right for you.
Initial174 mg orally once/dayafter 4 daysmay adjust to usual adult target dose of 348 mg orally once/day May increase not to exceed 522 mg once/day after more than 4 weeks.
Decreased memory3450 mg/daymay be increased risk with concomitant ECT)
Bupropion is an antidepressant medication that affects chemicals within the brain that nerves use to send messages to each otherThese chemical messengers are called neurotransmittersMany experts believe that depression is caused by an imbalance among the amounts of neurotransmitters that are releasedNervesin a process referred to as reuptakemay recycle released neurotransmittersBupropion works by inhibiting the reuptake of dopamineserotoninand norepinephrinean action that results in more dopamineserotoninand norepinephrine to transmit messages to other nervesBupropion is unique and unlike other antidepressants in that its major effect is on dopaminean effect that is not shared by the selective serotonin reuptake inhibitors or SSRIsfor exampleparoxetinePaxilfluoxetineProzacsertralineZoloftor the tricyclic antidepressants or TCAsfor exampleamitriptylineElavilEndepimipramineTofranildesipramineNorpraminThe FDA approved bupropion in December 1985.
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