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Tetracyclines in the blood plasma are transported as calcium complex that once inside the cells of the bacteriaforms a complex with magnesiumwhich binds to the ribosomeIn this regardit is known that the binding of the ribosome complex magnesium inhibits protein synthesis by triggering the bacteriostatic effectRocha et al.2011which do not kill the microorganismbut acts as preventing bacterial multiplication and are eliminated by the defense system of the patientMathers et al 2011
ZHAOYGENGJWANGXGUXGAOSAdsorption of tetracycline onto goethite in the presence of metal cations and humic substancesJColloid Interface Sci.v.361p.247-2512011aLinks
Bhaskar DasSanjukta Patrain Nanostructures for Antimicrobial Therapy2017.
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the most common tetracycline resistance mechanisms are efflux pumps and ribosome-protection proteins wilson, 2014 .
