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It does this by being a positive allosteric modulator of Acetylcholine which means that it increases the activation of receptors for this neurotransmitter in the brain.

Patients with kidney problems and impaired renal function are advised to take lower dosages of this drugdepending on their creatinine clearanceCLcrtest results.

Adjustment of the dose is recommended in elderly patients with compromised renal functionseeDosage adjustment in patients with renal impairmentbelowFor long term treatment in the elderlyregular evaluation of the creatinine clearance is required to allow dosage adaptation if needed.

Nootropil is also believed to increase blood flow to the brain and protect the cerebral cortex from low oxygen levels.

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there are a few studies that seem to indicate using nootropil may also help to slow the progression of this disease, although it would be too early to suggest that nootropil could be considered a cure.